Our technology

Preclinical safety

Good safety & pharmacokinetic profile

Our molecules are well tolerated* in in vivo settings both in acute and chronic conditions with good pharmacokinetic parameters, oral bioavailability, and cardiac safety.

Test passed:
- genotoxicity: in vitro micronucleus test in human lymphocytes
- mutagenicity: Ames Test in Salmonella Typhimurium and Escherichia coli
- oral bioavailability: comparative pharmacokinetic analysis in vivo versus gavage administration
- cardiac safety: hERG channel test

* according to the OECD guidelines and Good-Laboratory Practice (GLP) criteria

Patent filed

IP protection

ChemiCare holds exclusive patent life-long exploitation license rights on the following two patents filed by the University of Piemonte Orientale:
Click chemistry

Easy manufacturing

Our molecules have been synthesized through the click chemistry approach, which allows:
  • parallel preparation of a large number of molecules;
  • straightforward exploration of the chemical space during the early drug discovery phase;
  • easy chemical refinement of hit compounds during the hit-to-lead process in order to meet the pharmacokinetic and pharmacodynamic requirements.

Our pipeline

[Update January 2024]